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Study identifier: NCT07209761 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis

Condition: Pulmonary Tuberculosis  ·  Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

PhasePhase 3
Planned participants532
Who can joinAll sexes, 14 Years to no upper limit
Healthy volunteersNo

About this study

This study aims to assess quabodepistat-based treatment regimens for RR/MDR-TB. The study will enroll adults and adolescents with rifampicin-resistant or multidrug-resistant pulmonary TB. The main goal is to see if a new drug called quabodepistat, when combined with other TB drugs, can shorten treatment duration to 4 months and be as effective and safer than current WHO endorsed treatment regimen given for 6-months. The study will compare different drug combinations in two groups of patients: those whose TB is sensitive to fluoroquinolones and those whose TB is resistant to fluoroquinolones. Participants will be randomly assigned to receive either the new treatment or the standard treatment. The study will last for 16 months for each participant and will measure how well the treatments work and how safe they are.

This description comes directly from the study's public registry record.

Talk to the study team

Otsuka Call Center  ·  +1 844-687-8522  ·  Otsuka-ProfessionalServices@otsuka-us.com

Always discuss trial participation with your own doctor first.

Locations (35)

Capital Medical University - Beijing Chest HospitalBeijing, Beijing Municipality, ChinaRecruiting
Fuzhou Tuberculosis Prevention and Control Hospital of Fujian ProvinceFuzhou, Fujian, ChinaNot Yet Recruiting
The Third People's Hospital of ShenzhenShenzhen, Guangdong, ChinaNot Yet Recruiting
Wuhan Institute of Tuberculosis Control (Wuhan Pulmonary Hospital)Wuhan, Hubei, ChinaNot Yet Recruiting
The Second Hospital of NanjingNanjing, Jiangsu, ChinaNot Yet Recruiting
Shandong Public Health Clinical CenterJinan, Shandong, ChinaNot Yet Recruiting
Huashan Hospital Fudan UniversityShanghai, Shanghai Municipality, ChinaNot Yet Recruiting
Shanghai Pulmonary Hospital - PneumologyShanghai, Shanghai Municipality, ChinaNot Yet Recruiting
Public Health Clinical Center of ChengduChengdu, Sichuan, ChinaNot Yet Recruiting
National Center for Tuberculosis and Lung DiseaseTbilisi, GeorgiaRecruiting
Japan Anti-Tuberculosis Association Fukujuji HospitalKiyose, Tokyo, JapanNot Yet Recruiting
IMSP Institutul de Ftiziopneumologie Chiril Draganiuc - PhthisiopneumologyChisinau, Chisinau City, MoldovaRecruiting

+ 23 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07209761