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Study identifier: NCT07209462 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM)

Condition: Fragile X Syndrome  ·  Sponsor: Mirum Pharmaceuticals, Inc.

PhasePhase 2
Planned participants60
Who can joinMale, 13 Years to 45 Years
Healthy volunteersNo

About this study

This study is a multicenter, double-blind, randomized, placebo-controlled study to assess the safety and tolerability of 3 doses of MRM-3379 in male participants with Fragile X Syndrome ages 16 to 45 (inclusive). In addition, a parallel cohort of participants ages 13 to \<16 will receive open-label MRM-3379. All participants will participate for 12 weeks of treatment. The study is also intended as a proof-of-concept investigation to evaluate whether MRM-3379 can improve FXS symptoms

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (15)

Southwest Autism Research & Resource CenterPhoenix, Arizona, United StatesRecruiting
Amnova Clinical Research, LLCIrvine, California, United StatesRecruiting
Children's Hospital of Orange County - Pediatric SubspecialtyOrange, California, United StatesNot Yet Recruiting
Uc Davis Mind InstituteSacramento, California, United StatesRecruiting
Children's Hospital ColoradoAurora, Colorado, United StatesRecruiting
NeurologyMiami, Florida, United StatesNot Yet Recruiting
Emory University - The Emory Clinic - Clifton RoadAtlanta, Georgia, United StatesRecruiting
Rush University Medical Center-Clinical OperationChicago, Illinois, United StatesRecruiting
Kennedy Krieger Institute, John Hopkins School of MedicineBaltimore, Maryland, United StatesRecruiting
Boston Children's HospitalBoston, Massachusetts, United StatesRecruiting
UMass Memorial HealthWorcester, Massachusetts, United StatesRecruiting
University of Minnesota Department of MedicineMinneapolis, Minnesota, United StatesRecruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07209462