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Study identifier: NCT07209371 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Rifaximin Versus No Intervention for the Treatment of IgA Monoclonal Gammopathy of Undetermined Significance

Condition: IgA Monoclonal Gammopathy of Undetermined Significance  ·  Sponsor: Fred Hutchinson Cancer Center

PhasePhase 2
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial compares the effect of rifaximin to no intervention for the treatment of IgA monoclonal gammopathy of undetermined significance (MGUS). Rifaximin is a type of antibiotic that is only used in cancer chemotherapy (antineoplastic antibiotic). It works by damaging the cell's DNA and may kill cancer cells or precancerous cells like those found with MGUS. Giving rifaximin may kill more precancerous cells in patients with IgA MGUS.

This description comes directly from the study's public registry record.

Talk to the study team

Madhav Dhodapkar, MBBS  ·  206-606-4888  ·  mdhodapk@fredhutch.org

Always discuss trial participation with your own doctor first.

Locations (1)

Fred Hutch/University of Washington Cancer ConsortiumSeattle, Washington, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07209371