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Study identifier: NCT07209241 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Different Approaches for CART-EGFR-IL13Ra2 Dosing in Recurrent GBM

Condition: Recurrent Glioblastoma  ·  Sponsor: University of Pennsylvania

PhasePhase 1
Planned participants12
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is an open-label, phase 1b study to evaluate different approaches for CART-EGFR-IL13Ra2 dosing and further characterize the safety, feasibility, preliminary efficacy, and pharmacokinetics of CART-EGFR-IL13Ra2 cells in patients with EGFR-amplified glioblastoma that has recurred following prior radiotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Abramson Cancer Center Clinical Trials, MD, MSCE  ·  215-349-8245  ·  PMCancerResearch@pennmedicine.upenn.edu

University of Pennsylvania  ·  PMCancerResearch@pennmedicine.upenn.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07209241