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Study identifier: NCT07207954 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of LFD-200 in Healthy Adults and Adults With Moderate to Severe Rheumatoid Arthritis

Condition: Rheumatoid Arthritis  ·  Sponsor: Lifordi Immunotherapeutics, Inc.

PhasePhase 1
Planned participants176
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersYes

About this study

This is a double-blind, randomized, placebo- and active-controlled study investigating the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of subcutaneous (SC) doses of LFD-200. The study design includes: a single ascending dose (SAD) study in up to 66 adult healthy participants (HPs) to investigate the effects of a single SC dose, with a 30-day follow-up; a multiple ascending dose (MAD) study in up to 40 HPs to assess up to 4 weekly SC doses, with a 30-day follow-up after the last dose; and a MAD study in up to 70 participants with moderate to severe rheumatoid arthritis (RA) to evaluate up to 13 weekly SC doses, with a 30-day follow-up after the last dose.

This description comes directly from the study's public registry record.

Talk to the study team

Matthew McClure, MD  ·  +14158107700  ·  mmcclure@lifordi.com

Always discuss trial participation with your own doctor first.

Locations (7)

Nucleus NetworkMelbourne, AustraliaActive Not Recruiting
Arensia Exploratory Medicine LLCTbilisi, GeorgiaRecruiting
Clinical Republican Hospital "Timofei Mosneaga", ARENSIA E.M.Chisinau, MoldovaRecruiting
MICS Centrum Medyczne Torun - MICS - PPDSTorun, PolandNot Yet Recruiting
Centrum Medyczne Reuma ParkWarsaw, PolandNot Yet Recruiting
"ARENSIA EXPLORATORY MEDICINE" LIMITED LIABILITY COMPANY, Medical Center, Department of Clinical TrialsKyiv, UkraineRecruiting
Medical Clinical Investigational Center "Medical Center Health Clinic", LLCVinnytsia, UkraineRecruiting

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Source record: clinicaltrials.gov/study/NCT07207954