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Study identifier: NCT07206108 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Clinical Trial of Modified Endocrown and Personalized Post-core and Crown for Large-area Tooth Defects After Root Canal Treatment

Condition: Root Canal Infection · Tooth Defect · Post and Core Technique  ·  Sponsor: Nanfang Hospital, Southern Medical University

PhaseNA
Planned participants246
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

This study intends to adopt a multicenter, randomized controlled, single-blind, non-inferiority clinical trial design. 246 premolars that meet the inclusion criteria after complete root canal treatment will be selected from the clinical practice and randomly divided into two groups. One group will be restored with the modified endocrown, and the other group will be restored with personalized post and core combined with full crown. Follow-up visits were conducted at 6 months, 1 year and 2 years after the operation respectively. Through clinical and imaging examinations, the survival rates of the two different restorations were evaluated and used as the main evaluation indicators to fill the gap in efficacy data of the modified endocrown in clinical applications, providing a strong evidence-based medical basis for subsequent restoration improvement and standardized application.

This description comes directly from the study's public registry record.

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Locations (1)

Nanfang Hospital of Southern Medical UniversityChina, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07206108