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Study identifier: NCT07204418 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Evaluate the Effects of CYP2D6 Phenotypes on the Pharmacokinetics of Xanomeline Following KarXT Administration in Healthy Adult Participants

Condition: Healthy Volunteers  ·  Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

PhasePhase 1
Planned participants56
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

The purpose of this study is to evaluate the pharmacokinetics (PK) of xanomeline following administration of KarXT in CYP2D6 normal/extensive, intermediate, poor, and ultrarapid metabolizers.

This description comes directly from the study's public registry record.

Talk to the study team

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com  ·  855-907-3286  ·  Clinical.Trials@bms.com

First line of the email MUST contain the NCT# and Site #.

Always discuss trial participation with your own doctor first.

Locations (3)

Anaheim Clinical TrialsAnaheim, California, United StatesRecruiting
ICON - LenexaLenexa, Kansas, United StatesRecruiting
ICON Development SolutionsSan Antonio, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07204418