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Study identifier: NCT07204314 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Vortioxetine in Japanese Pediatric Patients With Major Depressive Disorder

Condition: Major Depressive Disorder  ·  Sponsor: Takeda

PhasePhase 3
Planned participants180
Who can joinAll sexes, 12 Years to 17 Years
Healthy volunteersNo

About this study

The main aim of the study is to check how well vortioxetine 10 mg/day or 20 mg/day works and to check for side effects compared to a placebo on depression symptoms in Japanese teenagers aged 12 to 17 years with a diagnosis of Major Depressive Disorder (MDD). The overall time each participant will be in the study is about 20 weeks. This includes up to 15 days (about 2 weeks) to check who can take part, a 14-week period where everyone receives vortioxetine or a placebo, and after that, a 4-week period to check for any side effects after treatment. During the study, participants will visit their clinic 13 times.

This description comes directly from the study's public registry record.

Talk to the study team

Takeda Contact  ·  +1-877-825-3327  ·  medinfoUS@takeda.com

Always discuss trial participation with your own doctor first.

Locations (30)

Nagoya City University HospitalNagoya, Aichi-ken, JapanRecruiting
Hirosaki University HospitalHirosaki, Aomori, JapanRecruiting
Kaku Mental ClinicChūōku, Fukuoka, JapanRecruiting
Jisenkai Nanko Psychiatric InstituteShirakawa, Fukushima, JapanRecruiting
Hokkaido University HospitalSapporo, Hokkaido, JapanRecruiting
NHO Shikoku Medical Center for Children and AdultsZentsujichó, Kagawa-ken, JapanRecruiting
St. Marianna University School of Medicine HospitalKawasaki, Kanagawa, JapanNot Yet Recruiting
Kanagawa Children's Medical CenterYokohama, Kanagawa, JapanRecruiting
Yokohama City University HospitalYokohama, Kanagawa, JapanRecruiting
Kochi Medical School HospitalNankoku, Kochi, JapanRecruiting
Tohoku University HospitalSendai, Miyagi, JapanNot Yet Recruiting
Miyakonojo Shinsei HospitalMiyakonojō, Miyazaki, JapanRecruiting

+ 18 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07204314