Condition: Chronic Urinary Tract Infection · Sponsor: University College, London
Chronic Urinary Tract Infection (UTI) is a type of UTI where symptoms are constant and occur every day, unlike recurrent UTIs, which come and go with symptom-free breaks in between. Current treatment for chronic UTI within the NHS is based on recommended guidelines for recurrent UTI. The standard approach typically includes one of the following treatments: * Long-term, prophylactic (low) dose daily antibiotic (where medication is used at low doses to try to prevent symptoms reoccurring). * Long-term use of a urinary antiseptic (which helps keep your urine bacteria free), called methenamine hippurate. These often do not work for people with chronic UTI, and symptoms can persist. Moreover, standard urine tests may fail to detect infections, making diagnosis and treatment more challenging. The EAT-UP trial will investigate whether longer courses of treatment (higher) dose antibiotics combined with methenamine hippurate (a urinary antiseptic) are a more effective treatment at reducing levels of infection and symptoms than standard of care treatments (as described above).
This description comes directly from the study's public registry record.
EAT-UP Trial Team · 020 3108 5298 · cctu.eat-up@ucl.ac.uk
Liz Deane · liz.deane@ucl.ac.uk
Always discuss trial participation with your own doctor first.
| University College London Hospital (UCLH), UCLH NHS Foundation Trust | London, United Kingdom | Recruiting |
| Whittington Hospital, Whittington Health NHS Trust | London, United Kingdom | Recruiting |
| St Mary's Hospital, Manchester University NHS Foundation Trust | Manchester, United Kingdom | Not Yet Recruiting |
| Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust | Newcastle upon Tyne, United Kingdom | Recruiting |
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT07202949