Condition: Hepatic Disorders · Intestinal Failure-associated Liver Disease · Cystic Fibrosis Liver Disease · Sponsor: Sahlgrenska University Hospital
The goal of this observational (diagnostic validation) study is to validate imaging-based biomarkers for assessing liver involvement in pediatric patients with established or suspected liver disease. The projekt involves 3 larger studies, each with specific aims specified in detailed description below. The main study (study 1) compares imaging-based biomarkers-with liver biopsy to evaluate their correlation with histologically confirmed liver disease, including fibrosis, inflammation, and steatosis. The main question the overall project aims to answer is: • Can multiple novel imaging-based biomarkers, such as shear wave elastography (SWE), shear wave dispersion (SWD), and attenuation imaging (ATI), be used for detailed, non-invasive liver characterization in children, and if so, how should they be used?
This description comes directly from the study's public registry record.
Hanna M Hebelka, Associate Prof. · +46705667867 · hanna.hebelka@vgregion.se
Charlotte de Lange, Assoc.Prof. · +46735367199 · charlotte.de.lange@vgregion.se
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| Department of Radiology, Queen Silvias Children´s Hospital,Gothenburg Sweden | Gothenburg, Västra Götaland County, Sweden | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07202910