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Study identifier: NCT07202884 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

Condition: Urinary Incontinence,Stress  ·  Sponsor: Eli Lilly and Company

PhasePhase 3
Planned participants1000
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The GZPS master protocol will support two independent studies, J2A-MC-GZS1 and J2A-MC-GZS2. Each study will see how well and safely orforglipron works in adult female participants with stress urinary incontinence (SUI) who have obesity or overweight. SUI is leaking urine during movement or activity such as coughing or exercising. Participation in the study will last about 58 weeks from screening to safety follow-up.

This description comes directly from the study's public registry record.

Talk to the study team

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or  ·  317-615-4559  ·  LillyTrials@Lilly.com

Physicians interested in becoming principal investigators please contact  ·  clinical_inquiry_hub@lilly.com

Always discuss trial participation with your own doctor first.

Locations (137)

University of Alabama -The Kirklin ClinicBirmingham, Alabama, United StatesRecruiting
AMR ClinicalMobile, Alabama, United StatesRecruiting
Urologic Surgeons of ArizonaMesa, Arizona, United StatesRecruiting
Matrix Clinical ResearchLos Angeles, California, United StatesRecruiting
Alarcon Urology CenterMontebello, California, United StatesRecruiting
Prestige Medical GroupTustin, California, United StatesCompleted
Colorado Clinical ResearchLakewood, Colorado, United StatesRecruiting
AMR ClinicalFort Myers, Florida, United StatesRecruiting
Altus ResearchLake Worth, Florida, United StatesRecruiting
New Age Medical Research CorporationMiami, Florida, United StatesRecruiting
Emerald Coast OBGYN Clinical ResearchPanama City, Florida, United StatesRecruiting
Teak Research ConsultsLawrenceville, Georgia, United StatesRecruiting

+ 125 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07202884