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Study identifier: NCT07202819 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Neoadjuvant Chemotherapy on MRI Accuracy Before Cystectomy

Condition: Muscle Invasive Bladder Cancer  ·  Sponsor: Assiut University

PhaseNA
Planned participants76
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if neoadjuvant chemotherapy (NAC) affects the accuracy of magnetic resonance imaging (MRI) in staging muscle-invasive bladder cancer (MIBC). This study will also assess how tissue changes induced by NAC impact MRI interpretation. The main questions it aims to answer are: Does NAC compromise the accuracy of MRI in staging MIBC? Does NAC-induced tissue change affect the reliability of MRI in tumor assessment? Researchers will compare MRI staging accuracy in MIBC patients who received NAC to those who went directly to surgery, to see if NAC impacts MRI's diagnostic performance. Participants will: Undergo MRI scanning before surgery Receive either NAC or go directly to surgery, depending on their group assignment Have their MRI results compared to histopathological outcomes after surgery

This description comes directly from the study's public registry record.

Talk to the study team

Hamza Elhashamy, MBBCh  ·  +201028635437  ·  Hamza.Ahmed00099@med.aun.edu.eg

Abdelrahman Abdelshafi, MBBCh  ·  +201123740500  ·  abdulrahman.18313572@med.aun.edu.eg

Always discuss trial participation with your own doctor first.

Locations (2)

Urology Department, Faculty of Medicine, Assiut UniversityAsyut, Asyut Governorate, EgyptNot Yet Recruiting
Urology Department, Faculty of Medicine, Assiut UniversityAsyut, Asyut Governorate, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT07202819