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Study identifier: NCT07202546 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)

Condition: HIV Infections  ·  Sponsor: ViiV Healthcare

PhasePhase 2
Planned participants186
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This clinical study is testing a new medication, VH4524184, to see if it can effectively treat HIV-1 in adults who have never received treatment for their infection. The study is comparing two different doses of VH4524184, each taken with the medications emtricitabine and tenofovir alafenamide (FTC/TAF), to a standard HIV treatment called dolutegravir and lamivudine (DTG/3TC). The purpose of the study is to provide data on the long-term antiviral activity of the VH4524184 and provide information regarding dosing formulation for further evaluations.

This description comes directly from the study's public registry record.

Talk to the study team

US GSK Clinical Trials Call Center  ·  877-379-3718  ·  GSKClinicalSupportHD@gsk.com

EU GSK Clinical Trials Call Center  ·  +44 (0) 20 89904466  ·  GSKClinicalSupportHD@gsk.com

Always discuss trial participation with your own doctor first.

Locations (123)

GSK Investigational SiteBakersfield, California, United StatesRecruiting
GSK Investigational SitePalm Springs, California, United StatesRecruiting
GSK Investigational SiteWest Hollywood, California, United StatesRecruiting
GSK Investigational SiteAurora, Colorado, United StatesRecruiting
GSK Investigational SiteNew Haven, Connecticut, United StatesRecruiting
GSK Investigational SiteFt. Pierce, Florida, United StatesRecruiting
GSK Investigational SiteHollywood, Florida, United StatesRecruiting
GSK Investigational SiteMiami, Florida, United StatesRecruiting
GSK Investigational SiteMiami Gardens, Florida, United StatesRecruiting
GSK Investigational SiteOakland Park, Florida, United StatesRecruiting
GSK Investigational SiteOrlando, Florida, United StatesRecruiting
GSK Investigational SiteOrlando, Florida, United StatesRecruiting

+ 111 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07202546