Condition: Large Infarct Core · Post-stroke Lymphocytopenia · Sponsor: YiLin
The efficacy and safety of early adjunctive methylprednisolone therapy in acute ischemic stroke patients with large infarct cores (ASPECTS score \< 6) and post-stroke lymphocytopenia remain unclear. These immunocompromised patients face higher mortality rates and poorer clinical outcomes, with limited effective treatment options currently available. This multicenter, randomized, double-blind, placebo-controlled, non-inferiority trial aims to demonstrate that early methylprednisolone administration combined with reperfusion therapy is non-inferior to placebo in terms of survival and functional outcomes at 90 days.
This description comes directly from the study's public registry record.
Yi Lin, MD · 86-13615039153 · linyi7811@163.com
Ying Fu, MD · 86-13920263588 · fuying1995@163.com
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| Department of Neurology, the First Affiliated Hospital Fujian Medical University | Fuzhou, Fujian, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07202143