Condition: Inspiratory Effort · Mechanical Ventilation · Major Abdominal Surgeries · Sponsor: Mahidol University
This physiological observational study will assess respiratory drive and inspiratory effort across varying levels of pressure support ventilation (PSV) in adult surgical ICU (SICU) patients after major abdominal surgery. By using non-invasive bedside indices (airway occlusion pressure at 100 ms after the onset of inspiration \[P0.1\], maximum negative occlusion pressure \[Pocc\], and pressure muscle index \[PMI\]), we aim to quantify how patients adapt to changes in ventilatory support and determine patterns of under- and over-assistance. Findings may inform optimal titration of PSV to reduce complications and improve clinical outcomes.
This description comes directly from the study's public registry record.
Nuanprae Kitisin, MD · +66896767706 · nuanprae.kit@mahidol.ac.th
Nattaya Raykateeraroj, MD · +66993519963 · nuanprae.kit@mahidol.ac.th
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| Faculty of Medicine, Siriraj Hospital, Mahidol University | Bangkok, Bangkoknoi, Thailand | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07199881