Condition: Mantle Cell Lymphoma (MCL) · Sponsor: Ruijin Hospital
This multicenter, open-label, trial aims to evaluate the efficacy and safety of orelabrutinib in combination with rituximab with optional autologous hematopoietic stem cell transplantation in patients with non-high-risk mantle cell lymphoma (MCL). The primary objective is to assess the optimal complete response (CR) rate during the induction phase, with secondary objectives including progression-free survival (PFS), overall survival (OS), objective response rate (ORR), and safety. Exploratory analysis will investigate the correlation between tumor biomarkers and treatment efficacy.
This description comes directly from the study's public registry record.
Li Wang · +862164370045 ext 610707 · wl11194@rjh.com.cn
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| Ruijin Hospital | Shanghai, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07199296