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Study identifier: NCT07196657 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Efficacy and Safety of Pregabalin and Crisugabalin in Patients With Fibromyalgia

Condition: Fibromyalgia · Pregabalin · Pain  ·  Sponsor: Beijing Tiantan Hospital

PhaseNA
Planned participants1116
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread pain, fatigue, and emotional disorders. Its onset is related to factors such as central sensitization and imbalance of neurotransmitters. The current mainstream treatments include pregabalin, but the efficacy of pregabalin is limited, with only 25%-40% pain relief rate, and adverse reactions are common. crisugabalin, a new highly selective α2δ ligand, has shown potential in animal models or preliminary clinical trials, but there is insufficient evidence for its application in FM. This study aims to explore the effectiveness and safety of pregabalin or crisugabalin in treating FM, with the aim of providing a better treatment option for FM patients.

This description comes directly from the study's public registry record.

Talk to the study team

Fang Luo, M.D.  ·  +86 13611326978  ·  13611326978@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Beijing Tiantan Hospital, Beijing, Beijing 100070Beijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07196657