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Study identifier: NCT07196644 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Assess Adverse Events and Change in Disease Activity in Participants 12 Years of Age or Older With Locally Advanced or Metastatic Solid Tumors That Harbor MET Amplification Receiving Intravenously Infused Telisotuzumab Adizutecan

Condition: Solid Tumors Harboring MET Amplification  ·  Sponsor: AbbVie

PhasePhase 2
Planned participants100
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess adverse events and change in disease activity of telisotuzumab adizutecan. Telisotuzumab adizutecan is an investigational drug being developed for the treatment of locally advanced or metastatic solid tumors that harbor MET amplification. This study will have 1 arm where participants will receive telisotuzumab adizutecan. Approximately 100 participants 12 years of age or older. with solid tumors harboring MET amplification will be enrolled in the study in up to 50 sites around the world. Participants will receive intravenous (IV) telisotuzumab adizutecan, as part of the 61.5 month study duration. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at an approved institution (hospital or clinic). The effect of the treatment will be frequently checked by medical assessments, blood tests, questionnaires and side effects.

This description comes directly from the study's public registry record.

Talk to the study team

ABBVIE CALL CENTER  ·  844-663-3742  ·  abbvieclinicaltrials@abbvie.com

Always discuss trial participation with your own doctor first.

Locations (37)

Beverly Hills Cancer Center /ID# 275465Beverly Hills, California, United StatesRecruiting
City of Hope National Medical Center /ID# 275613Duarte, California, United StatesRecruiting
Valkyrie Clinical Trials /ID# 275547Los Angeles, California, United StatesRecruiting
Yale University School of Medicine /ID# 275978New Haven, Connecticut, United StatesRecruiting
Florida Cancer Specialists - North /ID# 277137St. Petersburg, Florida, United StatesRecruiting
Northwestern University Feinberg School of Medicine /ID# 276436Chicago, Illinois, United StatesRecruiting
University of Chicago Medical Center /ID# 275342Chicago, Illinois, United StatesRecruiting
START Midwest /ID# 276603Grand Rapids, Michigan, United StatesRecruiting
Memorial Sloan Kettering Cancer Center - New York - York Avenue /ID# 275999New York, New York, United StatesRecruiting
Duke Cancer Institute /ID# 275604Durham, North Carolina, United StatesRecruiting
SCRI Oncology Partners /ID# 275686Nashville, Tennessee, United StatesRecruiting
Dell Seton Medical Center /ID# 276474Austin, Texas, United StatesRecruiting

+ 25 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07196644