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Study identifier: NCT07194551 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Assessing Uterine Cancer Risk in Lynch Syndrome Carriers Using Vaginal Self-sampling and a Health Questionnaire

Condition: Endometrial Cancer · Lynch Syndrome  ·  Sponsor: University of British Columbia

PhaseNA
Planned participants30
Who can joinFemale, 30 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this study is to find out if self-collected vaginal swabs can be used to detect early signs of uterine cancer or related conditions in people with Lynch syndrome (LS) who still have their uterus. The study also tests if people with LS are willing and able to collect these samples themselves and whether they find the process acceptable. The main questions this study asks are: * Will people with LS take part in self-collection of vaginal samples, and do they find it acceptable? * Can vaginal DNA mutations predict cancer risk or match results from other genetic or biopsy testing? * Can a cancer risk model used in the general population also help identify risk in people with LS? Participants will: * Answer a health questionnaire about lifestyle and symptoms * Collect their own vaginal swabs and measure their vaginal pH at home using a self-collection kit * Complete short surveys around the time of self-collection and at the end of the study

This description comes directly from the study's public registry record.

Talk to the study team

Aline Talhouk, PhD  ·  604-875-4111  ·  a.talhouk@ubc.ca

Research Assistant  ·  604-875-4111

Always discuss trial participation with your own doctor first.

Locations (1)

VGH Research PavilionVancouver, British Columbia, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT07194551