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Study identifier: NCT07193914 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Adaptation of the ECCCLORE Program for Patients With Addictive and Traumatic Problems

Condition: PTSD · Addiction · Substance Use Disorders  ·  Sponsor: Centre Hospitalier Universitaire de Nīmes

PhaseNA
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Complex posttraumatic stress disorder (cPTSD) is characterized by chronic and pervasive disruptions in emotion regulation, identity, and relationships following prolonged or multiple exposures to trauma. It is frequently found in patients with addiction. Individuals with cPTSD have more severe addiction. In addition, the co-occurrence of these two disorders is often associated with certain transdiagnostic processes such as impulsivity. Indeed, PTSD is linked to a higher impulsivity score, which in turn promotes increased substance use. A second process also associated with trauma and addiction is hostile attribution bias. Thus, the trauma-addiction comorbidity generates multiple behavioral consequences (aggression, increased substance use, etc.) that impact patients' quality of life and represent an important treatment target. Many authors and clinicians have worked on creating treatment programs targeting both disorders, although group format treatment lacks empirical support. Indeed, even though the Seeking Safety program has been shown to be effective in reducing PTSD symptoms and substance use, there is currently no evidence to suggest its superiority. The ECCCLORE program is a new 6-month cognitive behavioral therapy protocol initially designed for patients with borderline personality disorder, in whom addictive and traumatic issues are common. It is shorter than the standard dialectical behavioral therapy (DBT) program, which focuses on emotional dysregulation, impuls…

This description comes directly from the study's public registry record.

Talk to the study team

Laure Thebault  ·  06.80.13.54.39  ·  laure.thebault@chu-nimes.fr

Always discuss trial participation with your own doctor first.

Locations (1)

CHU de NîmesNîmes, Nîmes, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT07193914