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Study identifier: NCT07193641 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study on Using SFRT With Standard Treatment for Oligoprogressive NSCLC

Condition: Non Small Cell Lung Cancer  ·  Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

PhasePhase 2
Planned participants25
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if spatially fractionated radiotherapy (SFRT) combined with standard systemic therapy can treat oligoprogressive non-small cell lung cancer (NSCLC) in patients who have progressed after at least one line of systemic therapy. The main question it aims to answer is: \- Can the combination of SFRT and standard systemic therapy improve progression-free survival (PFS) compared to standard systemic therapy alone? Participants will: * Undergo SFRT treatment for oligoprogressive lesions, with specific dose fractionation determined by the radiation oncologist based on clinical parameters. * Continue their standard systemic therapy, which may include chemotherapy, targeted therapy, or immunotherapy, as adjusted by their treating physician. * Have regular follow-up assessments, including imaging studies to evaluate treatment response and monitor for disease progression.

This description comes directly from the study's public registry record.

Talk to the study team

Ting Zhang, phD.  ·  +8657187783521  ·  zezht@zju.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

2nd Affiliated Hospital, School of MedicineHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07193641