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Study identifier: NCT07192614 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Learn How Safe AZD6621 is, How Well it Works, and How it Moves Throughout the Body Over Time, in Adult Male Participants With Metastatic Prostate Cancer

Condition: Prostate Cancer  ·  Sponsor: AstraZeneca

PhasePhase 1/Phase 2
Planned participants52
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is being conducted to learn more about the safety, tolerability, and effectiveness of an experimental treatment for metastatic prostate cancer called AZD6621. The study is split into different modules which will look at AZD6621 delivered by different methods. The study is also further split into 2 parts, Part A which will test different dose levels of AZD6621 to determine which doses are the best in terms of safety and side effects (dose escalation), and Part B will further test at least two AZD6621 doses in a larger group of participants (dose expansion).

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (25)

Research SiteOrlando, Florida, United StatesRecruiting
Research SiteTampa, Florida, United StatesRecruiting
Research SiteBoston, Massachusetts, United StatesWithdrawn
Research SiteGrand Rapids, Michigan, United StatesRecruiting
Research SiteCommack, New York, United StatesRecruiting
Research SiteProvidence, Rhode Island, United StatesRecruiting
Research SiteGhent, BelgiumNot Yet Recruiting
Research SiteToronto, Ontario, CanadaNot Yet Recruiting
Research SiteQuébec, CanadaNot Yet Recruiting
Research SiteBeijing, ChinaRecruiting
Research SiteChengdu, ChinaSuspended
Research SiteGuangzhou, ChinaSuspended

+ 13 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07192614