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Study identifier: NCT07191795 Synced from ClinicalTrials.gov · July 28, 2026
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Uses of Phantom Sensations Induced by Global and Local Modifications of the Prosthetic Socket as Somatosensory Feedback During Walking in Lower Limb Amputees

Condition: Lower Limb Amputation  ·  Sponsor: Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est

PhaseNA
Planned participants228
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Following lower-limb amputation, the loss of somatosensory information from the missing limb renders walking less automatic, more cognitively demanding, and often asymmetric, which can lead to secondary pathologies. Hypothesis: This study is based on the hypothesis that phantom limb sensations (PLS), when coherent with the prosthetic device's movements and the phases of the gait cycle, can compensate for the loss of somatosensory feedback and thereby improve locomotion for individuals with amputation. It is further hypothesized that it is possible to artificially induce these coherent and useful sensations, notably through "referred sensations" elicited by stimulation of the residual limb (e.g., via the prosthetic socket). Objectives: The project aims to: * Determine whether the natural presence of phantom limb sensations during walking impacts gait parameters. * Confirm in a larger patient population that modifications to the prosthetic socket can induce or enhance phantom sensations that are perceived as useful for walking. * Investigate whether these perceptual changes (induced or enhanced) are associated with objective, measurable improvements in gait quality.

This description comes directly from the study's public registry record.

Talk to the study team

Jonathan J Pierret, PhD  ·  +33383526761  ·  jonathan.pierret@ugecam.assurance-maladie.fr

Christelle C Requena  ·  christelle.requena@ugecam.assurance-maladie.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Institut Régional de Médecine Physique et de RéadaptationNancy, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT07191795