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Study identifier: NCT07189208 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Evaluation of Antimicrobial Prophylaxis to Prevent Syphilis in Pregnancy in Patients at Risk in Rio de Janeiro, Brazil

Condition: Congenital Syphilis  ·  Sponsor: University of California, Los Angeles

PhasePhase 2
Planned participants500
Who can joinFemale, 18 Years to 45 Years
Healthy volunteersYes

About this study

The goal of this clinical trial is to learn if benzathine penicillin works to prevent maternal syphilis. It will also learn about the safety of benzathine penicillin. The main questions it aims to answer are: * Does benzathine penicillin lower the rate of syphilis in pregnancy? * What medical problems do participants have when taking benzathine penicillin? Researchers will compare benzathine penicillin to routine care to see if benzathine penicillin works to prevent syphilis. Participants will: * Take benzathine penicillin or receive routine care during the third trimester of pregnancy * Visit the clinic once a month for injections and tests * Report any reactions to benzathine penicillin to the study team

This description comes directly from the study's public registry record.

Talk to the study team

Karin Nielsen, MD  ·  310-825-5235  ·  knielsen@mednet.ucla.edu

Esaú C João, MD, PhD  ·  +55 (21) 2233-0018  ·  esaujoao@gmail.com

Always discuss trial participation with your own doctor first.

Locations (4)

Centro de Referencia e Atenção Especializada a Saúde da Mulher (CRAESM)Duque de Caxias, Rio de Janeiro, BrazilNot Yet Recruiting
Policlínica Hospital Municipal Duque de CaxiasDuque de Caxias, Rio de Janeiro, BrazilRecruiting
Unidade Básica de Saúde José de FreitasDuque de Caxias, Rio de Janeiro, BrazilNot Yet Recruiting
Hospital Federal dos Servidores do EstadoRio de Janeiro, Rio de Janeiro, BrazilRecruiting

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Source record: clinicaltrials.gov/study/NCT07189208