Condition: Multiple Myeloma · Hodgkin Lymphoma · Non-hodgkin Lymphoma · Sponsor: Thomas Jefferson University
This prospective trial investigates the approach of G-CSF with risk-adapted Plerixafor use for stem cell mobilization in patients undergoing autologous stem cell transplantation. Since FDA approval in 2008, Plerixafor has been combined with G-CSF to mobilize stem cells, though this regimen has been associated with a potentially higher incidence of engraftment syndrome. The trial aims to evaluate whether using G-CSF alone, with selective use of Plerixafor, can achieve adequate stem cell collection while possibly reducing the incidence of engraftment syndrome.
This description comes directly from the study's public registry record.
Xia Bi, MD, MS · 215-955-8874 · Xia.Bi@jefferson.edu
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| Thomas Jefferson University Hospital | Philadelphia, Pennsylvania, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07188090