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Study identifier: NCT07187778 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Phase II Trial of Single Agent Belzutifan or Pembrolizumab Versus Combination as Neoadjuvant Therapy in Clear Cell Renal Cell Carcinoma (BLAZE)

Condition: Clear Cell Renal Cell Carcinoma  ·  Sponsor: M.D. Anderson Cancer Center

PhasePhase 2
Planned participants10
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

To learn if belzutifan alone, pembrolizumab alone, or belzutifan and pembrolizumab in combination given before a total or partial nephrectomy (surgery to remove all or part of a kidney) can help to control locally advanced ccRCC.

This description comes directly from the study's public registry record.

Talk to the study team

Eric Jonasch, MD  ·  (713) 563-7232  ·  ejonasch@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

The University of Texas M. D. Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07187778