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Study identifier: NCT07187310 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

EXORA vs ESP Blocks in Laparoscopic Cholecystectomy

Condition: Postoperative Pain  ·  Sponsor: Fayoum University Hospital

PhaseNA
Planned participants114
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Laparoscopic cholecystectomy is still considered the gold standard for the surgical management of gallbladder disease due to its minimally invasive nature, shorter recovery time, and reduced postoperative complications. Despite these advantages, patients frequently experience moderate to severe postoperative pain, particularly in the early postoperative period, which can impede recovery, delay mobilization, and increase opioid consumption. Excessive opioid use after laparoscopic cholecystectomy is associated with several drawbacks, including nausea, vomiting, sedation, and delayed recovery. It also increases the risk of respiratory depression, especially in vulnerable patients, and may contribute to long-term opioid dependence. These risks highlight the importance of opioid-sparing strategies such as regional anesthesia techniques to improve patient outcomes and enhance recovery. Regional anesthesia techniques have emerged as essential components of multimodal analgesia strategies in abdominal surgeries. Among them, the Erector Spinae Plane (ESP) Block has gained popularity due to its relative ease of administration and favorable safety profile. Recently, a novel fascial plane block known as the EXORA block has been introduced as a promising alternative for abdominal wall analgesia. This block, which targets a different anatomical plane, is postulated to provide comparable or superior analgesic efficacy to traditional methods while maintaining safety and simplicity in execut…

This description comes directly from the study's public registry record.

Talk to the study team

Khaled M Sayed, Bch  ·  1065444158  ·  khaledm191170@gmail.com

Mohamed H Ragab, MD  ·  1090050298  ·  mhr02@fayoum.edu.eg

Always discuss trial participation with your own doctor first.

Locations (1)

Fayoum University hospitalEl Fayoum Qesm, Faiyum Governorate, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT07187310