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Study identifier: NCT07187180 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Evaluating the Clinical Efficacy of Thulio vs. Holmium Laser Enucleation of the Prostate

Condition: BPH With Symptomatic Lower Urinary Tract Symptoms · BPH With Urinary Obstruction  ·  Sponsor: Smita De

PhaseNA
Planned participants50
Who can joinMale, 18 Years to no upper limit
Healthy volunteersYes

About this study

Many consider laser enucleation of the prostate the new 'gold standard' for the surgical treatment of benign prostatic hyperplasia (BPH) due to its excellent outcomes, high success rates, and long-term efficacy. Holmium laser enucleation of the prostate (HoLEP) was the earliest form of prostate enucleation and is recommended by the American Urological Association (AUA), along with thulium laser enucleation of the prostate (ThuLEP), as size-independent techniques for the management of BPH with fewer complications than transurethral resection of the prostate (TURP). Further development of laser technology has additionally led to enucleation using pulsed-modulated (e.g. "Virtual Basket™" mode or MOSES™ mode) holmium lasers as well as the thulium fiber laser.

This description comes directly from the study's public registry record.

Talk to the study team

Iva Markovic  ·  216-636-9694  ·  markovi@ccf.org

Smita De, MD, PHD  ·  216-445-4818  ·  des@ccf.org

Always discuss trial participation with your own doctor first.

Locations (1)

Cleveland Clinic MainCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07187180