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Study identifier: NCT07186842 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9

Condition: Advanced Solid Cancers  ·  Sponsor: BioNTech SE

PhasePhase 1/Phase 2
Planned participants245
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main goal of this study is to evaluate the safety of BNT329 and to identify the best dose of BNT329. This will be done by measuring the number of side effects that participants experience and how severe they are. The second goal of this study is to evaluate how well BNT329 works. This will be done by measuring the number of participants who respond to the treatment. The length of time where the tumor does not grow or spread will also be measured. The study will also evaluate how BNT329 moves into, through, and out of the body and how the treatment affects the body.

This description comes directly from the study's public registry record.

Talk to the study team

BioNTech clinical trials patient information  ·  +49 6131 9084  ·  patients@biontech.de

Always discuss trial participation with your own doctor first.

Locations (16)

SCRI at HCA Health OneDenver, Colorado, United StatesRecruiting
Florida Cancer SpecialistsOrlando, Florida, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Monash HealthClayton, AustraliaRecruiting
Austin HealthHeidelberg, AustraliaRecruiting
St. Josef-Hospital im Katholischen Klinikum BochumBochum, GermanyRecruiting
Universitaetsklinikum UlmUlm, GermanyRecruiting
Hospital Universitari Vall d'HebronBarcelona, SpainRecruiting
Hospital San PedroLogroño, SpainRecruiting
Hospital Universitario HM Sanchinarro - START Madrid CIOCCMadrid, SpainRecruiting
Hospital Universitario Quironsalud Madrid - NEXT OncologyPozuelo de Alarcón, SpainRecruiting
St James´s University HospitalLeeds, United KingdomRecruiting

+ 4 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07186842