Condition: Stroke · Cerebrovascular Disorders · Brain Diseases · Sponsor: The Second Hospital of Anhui Medical University
Acute ischemic stroke (AIS) due to medium vessel occlusion (MeVO) or severe stenosis poses a significant clinical challenge. Recent large randomized controlled trials, DISTAL and ESCAPE-MeVO, demonstrated no significant benefit of endovascular therapy in patients with MeVO. Although intra-arterial thrombolysis has shown promise in clinical experience, robust evidence supporting its efficacy in MeVO or severe stenosis-related AIS is still absent. To fill this gap, the RESCUE MeVO trial has been designed as a multicenter, prospective, randomized, open-label, blinded end-point (PROBE) study to evaluate the efficacy and safety of intra-arterial thrombolysis in patients with AIS caused by MeVO or severe stenosis.
This description comes directly from the study's public registry record.
Qi Li, professor · +8618623511778 · qili_md@126.com
Always discuss trial participation with your own doctor first.
| Fu Yang People's Hospital | Fuyang, Anhui, China | Recruiting |
| Lin Quan People's Hospital | Fuyang, Anhui, China | Recruiting |
| The Second (Affiliated) Hospital of Anhui Medical University | Hefei, Anhui, China | Recruiting |
| Shucheng People's Hospital | Lu'an, Anhui, China | Recruiting |
| LiuZhou Worker's Hospital | Liuzhou, Guangxi, China | Recruiting |
| Lishui Central Hospital | Lishui, Zhejiang, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07185022