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Study identifier: NCT07184944 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

Condition: Crohn's Disease  ·  Sponsor: Sanofi

PhasePhase 3
Planned participants751
Who can joinAll sexes, 16 Years to 80 Years
Healthy volunteersNo

About this study

This is a multicenter, randomized, double-blind, placebo-controlled, maintenance, Phase 3 study to evaluate the efficacy and safety of duvakitug in participants with moderately to severely active Crohn's Disease (CD). Study details include: The study duration may be up to 286 weeks including: * 40-week Pivotal Maintenance Sub-Study * 240-week Open-Label Extension (OLE) Sub-Study * 45-day Follow-Up visit Note: For the participants who do not enroll into OLE Sub-Study, the duration will be up to 46 weeks, including the 40-week maintenance period and a 45-day follow-up visit. The treatment duration may be up to 280 weeks including: * 40 weeks in the Pivotal Maintenance Sub-Study * 240 weeks in OLE Sub-Study The total number of on-site visits will be up to 43: - 21 visits in the Pivotal Maintenance Sub-Study - 22 visits in the OLE Sub-Study

This description comes directly from the study's public registry record.

Talk to the study team

Trial Transparency email recommended (Toll free for US & Canada)  ·  800-633-1610  ·  Contact-US@sanofi.com

Always discuss trial participation with your own doctor first.

Locations (35)

Peak Gastroenterology Associates - Colorado Springs-Site Number: 8400039Colorado Springs, Colorado, United StatesRecruiting
Clinical Research of Osceola-Site Number: 8400013Kissimmee, Florida, United StatesRecruiting
Bioresearch Partner-Kendale Lakes-Site Number: 8400053Miami, Florida, United StatesRecruiting
NMC Research LLC-Site Number: 8400033Tampa, Florida, United StatesRecruiting
Gastroenterology Health Partners, PLLC - New Albany-Site Number: 8400100New Albany, Indiana, United StatesRecruiting
GI Alliance - Baton Rouge-Site Number: 8400129Baton Rouge, Louisiana, United StatesRecruiting
Texas Digestive Disease Consultants, PLLC d/b/a GI Alliance - Mandeville-Site Number: 8400128Mandeville, Louisiana, United StatesRecruiting
Gateway Gastroenterology-Site Number: 8400097St Louis, Missouri, United StatesRecruiting
MedTraits NY-Site Number: 8400045Maspeth, New York, United StatesRecruiting
NYU Langone Health-Site Number: 8400091New York, New York, United StatesRecruiting
Weill Cornell Medicine - NewYork-Presbyterian Hospital-Site Number: 8400040New York, New York, United StatesRecruiting
New York Gastroenterology Associates-Site Number: 8400009New York, New York, United StatesRecruiting

+ 23 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07184944