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Study identifier: NCT07181837 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase 1/2 Study of the Safety and Efficacy of MVX-220 in Angelman Syndrome

Condition: Angelman Syndrome  ·  Sponsor: MavriX Bio, LLC

PhasePhase 1/Phase 2
Planned participants12
Who can joinAll sexes, 4 Years to 50 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety and efficacy of MVX-220 gene therapy in children and adults with Angelman syndrome with UBE3A gene deletion, uniparental disomy, or imprinting center defect genotypes.

This description comes directly from the study's public registry record.

Talk to the study team

MavriX Bio, LLC  ·  978-538-8554  ·  info@mvxbio.com

Always discuss trial participation with your own doctor first.

Locations (3)

Cedars-Sinai Medical CenterLos Angeles, California, United StatesRecruiting
Rush University Medical CenterChicago, Illinois, United StatesRecruiting
Boston Children's HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07181837