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Study identifier: NCT07180927 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

DLL3 CAR-T Therapy Targeting Brain Tumors

Condition: Glioblastoma of Cerebellum  ·  Sponsor: Shenzhen Geno-Immune Medical Institute

PhasePhase 1/Phase 2
Planned participants30
Who can joinAll sexes, 2 Years to 70 Years
Healthy volunteersNo

About this study

The purpose of this study is to assess the feasibility, safety and efficacy of Delta-like ligand 3 (DLL3)-specific CAR-T cell therapy in patients with DLL3 positive brain tumors including glioblastomas and diffused intrinsic pontine or midline gliomas (DIPG or DMG). Another goal of the study is to learn more about the function of the anti-DLL3 CAR-T cells and their persistency in patients.

This description comes directly from the study's public registry record.

Talk to the study team

Lung-Ji Chang, PhD  ·  +86 0755-86573763  ·  c@szgimi.org

Always discuss trial participation with your own doctor first.

Locations (1)

Shenzhen Geno-immuno Medical InstituteShenzhen, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07180927