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Study identifier: NCT07180524 Synced from ClinicalTrials.gov · July 28, 2026
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Prospective Clinical Trial on the Impact of Uterine Firomatosis on Pelvic Floor.

Condition: Pelvic Floor Dysfunction · Fibromatosis  ·  Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia

PhaseN/A
Planned participants200
Who can joinFemale, 35 Years to 55 Years
Healthy volunteersYes

About this study

Uterine fibromatosis is one of the most frequent gynecological conditions; in fact, uterine fibroids involve approximately 25-30% of women during the fertile period. Risk factors for the development of this pathology include age, family history and ethnicity. Multiparity, advanced age for pregnancy and smoking appear to be protective factors. Myomas are responsible for numerous symptoms reported by patients, such as menometrorrhagia, pelvic pain and urinary and/or deficatory symptoms. Although myomas are asymptomatic in almost 50% of cases, they represent the first cause of hysterectomy for benign pathologies (about 2/3 of cases). Urinary symptoms associated with myomas are rarely studied in patients with symptomatic uterine fibromatosis; therefore the impact that this pathology has on the symptoms related to pelvic-perineal dysfunction and what their prevalence is is not well known at present. The prevalence of urinary symptoms in women with uterine myomas is highly variable based on literature data and the studies considered; in fact, the most frequently reported urinary symptoms are urinary urgency (31-59%), dysuria (4-36%) and stress urinary incontinence (20-80%). Furthermore, there is currently no unanimous agreement between the topography and size of myomas and related urinary and pelvic symptoms. The type of treatment varies from single or multiple myomectomy to hysterectomy performed laparoscopically or laparotomy. The choice of surgical approach depends on the numb…

This description comes directly from the study's public registry record.

Talk to the study team

Arsenio Spinillo  ·  +39382503267  ·  spinillo@smatteo.pv.it

Always discuss trial participation with your own doctor first.

Locations (1)

Fondazione IRCCS Policlinico San Matteo, SC Ostetricia e Ginecologia 1Pavia, Pavia, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07180524