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Study identifier: NCT07178847 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

cDNA and Residual Disease After Chemoradiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinomas

Condition: Locally Advanced Head and Neck Carcinoma  ·  Sponsor: Centre Jean Perrin

PhaseNA
Planned participants59
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The goal of this ancillary clinical trial is to evaluated circulating DNA as a biomarker of residual disease after chemoradiotherapy for locally advanced head and neck squamous cell carninoma. The main question it aims to answer is : \- Does circulating DNA (cDNA) be able to detect residual disease 3 months after the end of chemoradiotherapy ? Researchers will compare detection of cDNA at 3-months and objective response (clinical and radiological). Participants will : * be included in the main study (Neck-TAR) * have a blood sample 1 and 3-month after the end of treatment

This description comes directly from the study's public registry record.

Talk to the study team

Angeline GINZAC COUVÉ Project manager, PhD  ·  0463663337  ·  angeline.ginzac@clermont.unicancer.fr

Always discuss trial participation with your own doctor first.

Locations (4)

CH Henri Mondor AurillacAurillac, CANTAL, FranceRecruiting
Centre Jean PERRINClermont-Ferrand, Puy-de-Dôme, FranceRecruiting
Hôpital de la Croix-RousseLyon, FranceRecruiting
CHU de Saint-ÉtienneSaint-Etienne, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT07178847