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Study identifier: NCT07176923 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

CS-121 APOC3 Base Editing in FCS

Condition: Familial Chylomicronemia Syndrome (FCS)  ·  Sponsor: CorrectSequence Therapeutics Co., Ltd

PhaseEARLY_Phase 1
Planned participants15
Who can joinAll sexes, 18 Years to 55 Years
Healthy volunteersNo

About this study

This is an open-label, single-arm, dose-escalation Phase I clinical trial to evaluate the safety, tolerability, pharmacodynamics (PD), and pharmacokinetics (PK) of CS-121, an in vivo base editing therapy delivered by lipid nanoparticles targeting APOC3, in adult participants (18-55 years) with familial chylomicronemia syndrome (FCS).

This description comes directly from the study's public registry record.

Talk to the study team

Yaliang Li  ·  +8618621046122  ·  yaliang.li@correctsequence.com

Always discuss trial participation with your own doctor first.

Locations (1)

The First Affiliated Hospital of Anhui Medical UniversityHefei, Anhui, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07176923