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Study identifier: NCT07176507 Synced from ClinicalTrials.gov · July 29, 2026
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MULTIVALVE : A Prospective Multicentre Study of Multiple and Mixed Valvular Heart Disease

Condition: Valvular Heart Disease  ·  Sponsor: French Cardiology Society

PhaseN/A
Planned participants1000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Multiple and mixed valvular heart disease (MMVD) is a common condition in clinical practice. It corresponds to a combination of stenotic or leaky lesions on two or more heart valves (multiple valve disease), or a combination of stenotic and leaky lesions on the same valve (mixed valve disease). However, the management of their clinical, biological and cardiovascular imaging is not well established. Current European Society of Cardiology (ESC) recommendations primarily address the various valve diseases in isolation. This results in an absence of reliable recommendations for managing MMVD, with different approaches being adopted by care centres. In order to address this knowledge gap regarding MMVD, it is crucial to assess its prevalence, the cardiovascular imaging methods employed and the management strategies, as well as to identify prognostic factors for the various combinations of valve disease. The multicentre MMVD study will be a valuable resource as it will improve our understanding of the prognosis for patients with MMVD. It will highlight imaging and biological markers associated with the prognosis of different combinations of MMVD.

This description comes directly from the study's public registry record.

Talk to the study team

Théo PEZEL  ·  01 44 90 70 28  ·  multivalve@sfcardio.fr

Augustin COISNE  ·  01 44 90 70 28  ·  multivalve@sfcardio.fr

Always discuss trial participation with your own doctor first.

Locations (2)

Chu Lille- Hopital CardiologiqueLille, FranceRecruiting
Chu Lariboisiere (Aphp)Paris, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT07176507