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Study identifier: NCT07175428 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation

Condition: Atrial Fibrillation (AF)  ·  Sponsor: Regeneron Pharmaceuticals

PhasePhase 2
Planned participants1200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is researching experimental drugs called REGN7508 and REGN9933. The study is focused on participants who have atrial fibrillation, which means that the heart beats too fast and unevenly. REGN7508 and REGN9933 are designed to help stop blood clots forming in patients with atrial fibrillation. The aim of the study is to see how well REGN7508 and REGN9933 work in patients that get medicine for their atrial fibrillation. The bleeding effects of REGN7508 and REGN9933 will be compared to another medicine (apixaban), which is available on the market to treat and prevent formation of blood clots. The study is looking at several other research questions, including: * What side effects may happen from taking REGN7508 or REGN9933 * How well do the study drugs reduce the risk of having a stroke * How much of REGN7508 or REGN9933 is in the blood at different times * Whether the body makes antibodies against REGN7508 or REGN9933 (which could make the drugs less effective or could lead to side effects)

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials Administrator  ·  844-734-6643  ·  clinicaltrials@regeneron.com

Always discuss trial participation with your own doctor first.

Locations (70)

SEC Clinical ResearchDothan, Alabama, United StatesRecruiting
Eastern Shore Research InstituteFairhope, Alabama, United StatesRecruiting
Valley Clinical Trials, IncCovina, California, United StatesRecruiting
North Coast CardiologyEncinitas, California, United StatesRecruiting
Mission Cardiovascular Research InstituteFremont, California, United StatesRecruiting
National Institute of California Heart and Vein SpecialistsHuntington Beach, California, United StatesRecruiting
Profound Research LLC at Southern California Heart SpecialistsPasadena, California, United StatesRecruiting
Empire Clinical ResearchPomona, California, United StatesRecruiting
Northbay Clinical Research CenterSanta Rosa, California, United StatesRecruiting
Cardiology Associates Medical GroupVentura, California, United StatesRecruiting
Interventional Cardiology Medical GroupWest Hills, California, United StatesRecruiting
Nouvelle Clinical Research LLCCutler Bay, Florida, United StatesRecruiting

+ 58 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07175428