Condition: Out of Hospital Cardiac Arrest · Ventricular Fibrillation · Defibrillation · Sponsor: Gabriel Riva
Some of the patients affected by Out-of-hospital cardiac arrest (OHCA) with ventricular fibrillation (VF)/ventricular tachycardia (VT) do not respond to initial defibrillation. The survival decreases with number of defibrillations required to terminate VF/VT. In 2022, one prospective cluster randomized trial showed increased survival among (OHCA) patients in refractory VF using Double Sequential Defibrillation (DSD). If DSD can increase survival among all patients in VF that dont respond to one defibrillation, i.e. before it has become refractory is not known. The aim of this trial is to assess survival with a double defibrillation strategy initiated as soon as possible among patients with Out of Hospital Cardiac Arrest with initial shockable rhythm and at least one failed standard defibrillation, compared with continued resuscitation using standard defibrillation.
This description comes directly from the study's public registry record.
Gabriel Riva, M.D. Ph.D · + 47 70 545 20 86 · gabriel.riva@ki.se
Akil Awad, M.D. Ph.D. · (+46) 070 400 13 63 · akil.awad@ki.se
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| ARREST (AmsteRdam REsuscitation STudies) | Amsterdam, Netherlands | Not Yet Recruiting |
| Centro de Emergencias 061 Andalucía | Málaga, Andalusia, Spain | Not Yet Recruiting |
| Médico Emergencias Osakidetza EMERGENTZIAK | Bilbao, Baque Country, Spain | Not Yet Recruiting |
| Sistema de Emergencias Medicas de Catalunya | Barcelona, Catalonia, Spain | Not Yet Recruiting |
| SUMMA 112 Emergency medical services | Madrid, Madrid, Spain | Not Yet Recruiting |
| Ambulanssjukvården, Region Halland | Halmstad, Halland County, Sweden | Recruiting |
| Ambulanssjukvården Region Värmland | Karlstad, Värmland County, Sweden | Recruiting |
| Ambulanshelikoptern (HEMS) Västra Götalandsregionen | Kungälv, Västra Götaland County, Sweden | Recruiting |
| Sjukvården i väster | Alingsås, Sweden | Recruiting |
| Emergency medical services, Södra Älvsborgs Sjukhus, Region Västra Götaland | Borås, Sweden | Recruiting |
| Prehospital Intensive Care Unit (PIV) AnOPIVA Östra Sjukhuset/SU | Gothenburg, Sweden | Recruiting |
| Shalgrenska University Hospital | Gothenburg, Sweden | Recruiting |
+ 2 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07174986