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Study identifier: NCT07174310 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

Condition: Parkinson's Disease  ·  Sponsor: Hoffmann-La Roche

PhasePhase 3
Planned participants900
Who can joinAll sexes, 50 Years to 85 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics (PK) of prasinezumab compared with placebo in participants with early-stage Parkinson's disease (PD) on stable symptomatic monotherapy with levodopa.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: BN44715 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728 (U.S. and Canada)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (174)

University of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting
Barrow Neurological InstitutePhoenix, Arizona, United StatesRecruiting
Neurology Center of North Orange CountyFullerton, California, United StatesRecruiting
UC San DiegoLa Jolla, California, United StatesRecruiting
Keck School of Medicine of USCLos Angeles, California, United StatesRecruiting
UCLA Neurology Outpatient ClinicLos Angeles, California, United StatesRecruiting
Parkinson?s Research Centers of America ? Palo AltoPalo Alto, California, United StatesRecruiting
Profound Research LLC at The Neurology Center of Southern CaliforniaPasadena, California, United StatesRecruiting
UCSF Weill Institute for NeurosciencesSan Francisco, California, United StatesRecruiting
Rocky Mountain Movement DisordersEnglewood, Colorado, United StatesRecruiting
Institute for Neurodegenerative DisordersNew Haven, Connecticut, United StatesRecruiting
Georgetown UniversityWashington D.C., District of Columbia, United StatesRecruiting

+ 162 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07174310