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Study identifier: NCT07173504 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Effect of Continuous Versus Intermittent Enteral Nutrition on Metabolic Outcomes in Critically Ill Patients

Condition: Critical Illness  ·  Sponsor: Gelderse Vallei Hospital

PhaseNA
Planned participants124
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to investigate the effect of continuous versus intermittent enteral nutrition on metabolic outcomes in critically ill adult patients. The aim of this study is to: • To assess the effect of a daytime intermittent tube feeding pattern compared to standard continuous tube feeding on glycaemic control, gastrointestinal function, gastrointestinal hormones, markers of sleep quality and circadian rhythm, and lean body mass and body composition. Participants will receive either continuous enteral nutrition for 24 hours a day or intermittent enteral nutrition during the day, consisting of 4 portions each administered over 1 hour between 8 am and 8 pm. The maximum duration of the intervention is 5 days or until participants do not receive exclusive gastric enteral nutrition.

This description comes directly from the study's public registry record.

Talk to the study team

Arthur RH van Zanten  ·  +3131843115  ·  ZantenA@zgv.nl

Imre WK Kouw  ·  imre.kouw@wur.nl

Always discuss trial participation with your own doctor first.

Locations (5)

Gelderse Vallei HospitalEde, Gelderland, NetherlandsRecruiting
Deventer ZiekenhuisDeventer, Overijssel, NetherlandsRecruiting
Medisch Spectrum TwenteEnschede, Overijssel, NetherlandsRecruiting
Martini ZiekenhuisGroningen, Provincie Groningen, NetherlandsRecruiting
Haga ZiekenhuisThe Hague, South Holland, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT07173504