Condition: Duchenne Muscular Dystrophy (DMD) · Sponsor: Vanderbilt University Medical Center
This is a pharmacokinetic study (PK Study) to better understand empagliflozin dosing in pediatric Duchenne muscular dystrophy patients. Empagliflozin is currently used off-label in this population due to the mortality benefits seen in adult cardiomyopathy and heart failure. Investigators will perform PK studies in DMD patients of various ages and weights to better understand the PK profile (absorption, distribution, metabolism, excretion) and dosing to better treat Duchenne cardiomyopathy.
This description comes directly from the study's public registry record.
Larry W Markham, MD · 615 322-7447 · larry.w.markham@vumc.org
Jennifer B Nicotera, RN · 615 322-7447 · janet.b.nicotera@vumc.org
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| Vanderbilt University Medical Center | Nashville, Tennessee, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07172971