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Study identifier: NCT07172659 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy and Safety Study of Dovramilast in People With Leprosy Type 2 Reaction

Condition: Erythema Nodosum Leprosum  ·  Sponsor: Medicines Development for Global Health

PhasePhase 2
Planned participants45
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Dovramilast has not been approved for leprosy type 2 reaction (erythema nodosum leprosum, ENL) or any other disease anywhere in the world. In this study, an experimental drug called dovramilast is being tested to see how it compares to current treatments for leprosy type 2 reaction. Specifically, this study aims to assess the efficacy of 100mg or 150 mg dovramilast compared with standard treatments (also known as standard of care). This study also aims to assess the safety of two strengths in adults with leprosy type 2 reaction.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (6)

Harborview Medical Center, University of WashingtonSeattle, Washington, United StatesNot Yet Recruiting
Centre de Dépistage de Traitement de la Lèpre et de l'Ulcère de BurulliAbomey-Calavi, BeninNot Yet Recruiting
Chr de DivoDivo, Côte d’IvoireNot Yet Recruiting
Universitas Gadjah MadaYogyakarta, IndonesiaNot Yet Recruiting
Programme national lutte contre la lèpreTôlanaro, MadagascarNot Yet Recruiting
Philippine General Hospital, University of the Philippines, ManilaManila, PhilippinesRecruiting

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Source record: clinicaltrials.gov/study/NCT07172659