Condition: VHL - Von Hippel-Lindau Syndrome · Sponsor: IRCCS Ospedale San Raffaele
The study is a phase 2, non-comparative and non-randomized, single arm, national clinical trial testing the hypothesis that CAIX-PET has diagnostic and theranostic potential in VHL disease and in VHL-/- tumors. Participants will receive a single dose of the diagnostic radiopharmaceutical \[89Zr\]Zr-DFO-Girentuximab and subsequently will be subjected to imaging with an hybrid PET/CT scanner. Sensitivity and diagnostic accuracy of experimental imaging will be assessed against standard of truth derived from standard of care procedures such as MRI or pathology following surgery. A theranostic approach will be simulated by replacing the physical decay of the diagnostic isotope \[89Zr\]Zr with the physical decay of therapeutic isotopes and evaluating tissue dosimetry.
This description comes directly from the study's public registry record.
Alessandro Larcher · +39 02.2643.4121 · larcher.alessandro@hsr.it
Always discuss trial participation with your own doctor first.
| IRCCS Ospedale San Raffaele | Milan, Italia, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07171905