Condition: Mechanical Power · Postoperative Pulmonary Complications (PPCs) · Oxygenation · Sponsor: Pest County Flór Ferenc Hospital
The goal of this randomized controlled clinical trial is to compare the pulmonary protective effects of two different positive end-expiratory pressure (PEEP) titrating methods in patients with non-injured lungs undergoing laparoscopic gynecological surgery. Despite dynamic pulmonary compliance (Cdyn) guided lung protective ventilation has several proven advantages, the investigators hypothesize that optimizing intraoperative mechanical ventilation using electrical impedance tomography (EIT) may further improve patient outcomes, enhance postoperative recovery, shorten in-hospital stay and reduce healthcare related costs. The main questions aim to answer are: * May EIT-guided PEEP titration reduce the mechanical power of ventilation and improve oxygenation more significantly than the Cdyn-guided method? * What effect might a decrease in mechanical power of ventilation have on postoperative pulmonary complications? Participants will: * Receive an EIT-guided or a Cdyn-guided PEEP titration procedure during laparoscopic gynecological surgery. * Be assessed for mechanical power of ventilation, oxygenation, atelectasis and postoperative pulmonary complications during and 2 days after surgery. * Be followed-up for mortality until the 28th postoperative day.
This description comes directly from the study's public registry record.
Zoltán Ruszkai, MD, PhD · 36-20-915-1978 · ruszkai.zoltan@florhosp.hu
Gergely Bokrétás, MD · bokretas.gregely@florhosp.hu
Always discuss trial participation with your own doctor first.
| Semmelweis University | Budapest, Budapest, Hungary | Not Yet Recruiting |
| Semmelweis Hospital Kiskunhalas | Kiskunhalas, Bács-Kiskun county, Hungary | Not Yet Recruiting |
| Flór Ferenc Hospital Kistarcsa | Kistarcsa, Pest County, Hungary | Recruiting |
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT07170514