Condition: Ankylosing Spondylitis · Sponsor: Saglik Bilimleri Universitesi
Subclinical intestinal inflammation and intestinal permeability have been reported in patients with ankylosing spondylitis. Gluten is one of the main triggers of zonulin releaseand gluten intake may contribute to the development of the disease by increasing intestinal permeability. This study aims to determine the impacts of a gluten-freediet on intestinal permeability, sub-clinical intestinal inflammation, disease activity, functional status and quality of life in patients with ankylosing spondylitis. The main questions it aims to answer are: Does a gluten-free diet have an effect on disease activity and functional status in patients with ankylosing spondylitis? Does a gluten-free diet have an effect on intestinal permeability and subclinical intestinal inflammation in patients with ankylosing spondylitis? The investigators will evaluate the effects of the gluten-free diet compared to a control group.
This description comes directly from the study's public registry record.
Gülay Sezgin · +902124147171 · dytgulaysezgin@gmail.com
Always discuss trial participation with your own doctor first.
| Bakırköy Dr. Sadi Konuk Training and Research hospital | Istanbul, Turkey (Türkiye) | Recruiting |
| İstanbul Medeniyet University | Istanbul, Turkey (Türkiye) | Active Not Recruiting |
| İstanbul Sağlık Bilimleri University | Istanbul, Turkey (Türkiye) | Active Not Recruiting |
| Marmara University | Istanbul, Turkey (Türkiye) | Active Not Recruiting |
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Source record: clinicaltrials.gov/study/NCT07166874