Condition: Mild Traumatic Brain Injury, Concussion · Post Concussive Syndrome, Chronic · Post Traumatic Headache · Sponsor: Reuth Rehabilitation Hospital
Background: Mild Traumatic Brain Injury (mTBI) often results in persistent emotional, cognitive, and somatic symptoms-such as headaches and dizziness. These symptoms impose a significant burden, yet their underlying mechanisms remain unclear. Predictive processing theories suggest that persistent symptoms may result from learned perceptual errors, particularly in individuals with high negative affectivity. This framework may help explain ongoing persistent post-concussive symptoms (PPCS) in the absence of identifiable pathology, which have been linked to various psychological factors. Mental imagery (MI) is thought to engage similar predictive processes. There is evidence that MI of symptom-triggering movements may exacerbate symptoms in individuals with chronic somatic conditions. However, this phenomenon has not been studied in PPCS patients. Investigating symptom provocation through MI may yield novel insights into the neuropsychological mechanisms sustaining PPCS and potentially contribute to the development of therapeutic tools for this population. Objectives: 1. Documenting the exacerbation of headache and dizziness following provocative mental imagery (imagery of movements or scenarios that elicit these symptoms in real life) in patients with PPCS. 2. Comparing changes in headache and dizziness after provocative MI versus neutral MI (imagery of movements or scenarios that do not elicit these symptoms in real life). 3. Comparing patients who experience symptom exace…
This description comes directly from the study's public registry record.
Yotam Yanai, BPT · 972523993918 · yanayot@gmail.com
Gali Pinsky, BPT · 972546326566 · galipinsky95@gmail.com
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| Reuth Rehabilitation Hospital | Tel Aviv, Israel | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07166536