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Study identifier: NCT07162675 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Step Count and Treatment Response in Neoadjuvant Breast Cancer

Condition: Breast Neoplasm Malignant Female · Exercise · Breast Cancer Females  ·  Sponsor: Ankara Etlik City Hospital

PhaseN/A
Planned participants82
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This prospective multicenter observational study (NEOBRE-STEP) investigates the impact of daily step counts, measured by Huawei Fit 2 smartwatches, on treatment response in patients with non-metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-negative breast cancer undergoing neoadjuvant systemic therapy. Patients will wear smartwatches to continuously record step counts, activity intensity, sleep, and heart rate. Patient-reported outcomes, including sleep quality (Pittsburgh Sleep Quality Index, PSQI) and quality of life (European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire - Core 30, EORTC QLQ-C30), will be assessed at baseline and after treatment. The primary outcomes are pathological complete response (pCR) and Miller-Payne score. Secondary outcomes include sleep quality, quality of life, perioperative outcomes, and feasibility of smartwatch monitoring.

This description comes directly from the study's public registry record.

Talk to the study team

Galip Can Uyar, MD  ·  +905065963812  ·  g.can_uyar@hotmail.com

Ömür Berna Öksüzoğlu, MD  ·  +905055718475  ·  bernaoksuzoglu@yahoo.com

Always discuss trial participation with your own doctor first.

Locations (2)

Etlik City Hospital, Medical Oncology DepartmentAnkara, Yenimahalle, Turkey (Türkiye)Recruiting
Gazi University Medical Oncology DepartmentAnkara, Çankaya, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07162675