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Study identifier: NCT07161258 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Pharmacokinetics (PK), Pharmacodynamics (PD), Safety and Tolerability Study of Fenebrutinib in Children and Adolescents With Relapsing Multiple Sclerosis (RMS)

Condition: Relapsing Multiple Sclerosis  ·  Sponsor: Hoffmann-La Roche

PhasePhase 2
Planned participants12
Who can joinAll sexes, 10 Years to 17 Years
Healthy volunteersNo

About this study

This open label, single arm study will evaluate the PK and PD effects of fenebrutinib in children and adolescents with RMS aged between 10 and \< 18 years. This study consists of a Dose Exploration Period and an Optional Extension Period. Eligible participants may choose to continue treatment with fenebrutinib in the optional extension period after completing the dose exploration period.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: CN45847 https://forpatients.roche.com/  ·  888-662-6728 (U.S.)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. No email attachments. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (17)

INECO Neurociencias OronoRosario, Santa Fe Province, ArgentinaRecruiting
Sanatorio del Sur S.A.San Miguel de Tucumán, ArgentinaRecruiting
L2IP ?Instituto de Pesquisas Clínicas Ltda.Brasília, Federal District, BrazilRecruiting
Instituto de Neurologia de Curitiba - Hospital EcovilleCuritiba, Paraná, BrazilRecruiting
Nucleo de Pesquisa Clinica do Rio Grande do Sul NPCRPorto Alegre, Rio Grande do Sul, BrazilRecruiting
Centro de Pesquisas Clinicas - CPCLINSão Paulo, São Paulo, BrazilRecruiting
Clinstile S.A de C.V.Mexico City, Mexico CITY (federal District), MexicoRecruiting
Neurociencias Estudios Clinicos S.C.Culiacán, Sinaloa, MexicoRecruiting
Uniwersyteckie Centrum KliniczneGdansk, PolandRecruiting
Uniwersytecki Szpital Kliniczny w PoznaniuPoznan, PolandRecruiting
Instytut "Pomnik - Centrum Zdrowia Dziecka"Warsaw, PolandRecruiting
Centro Clnico Acadmico - Braga, Associao (2CA-Braga)Braga, PortugalRecruiting

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07161258