Condition: Asthma (Diagnosis) · OSA - Obstructive Sleep Apnea · CPAP Treatment · Sponsor: St. James's Hospital, Ireland
The OSADA (Obstructive Sleep Apnoea in Difficult Asthma) trial is an open-label, randomized control trial investigating the impact of diagnosing and treating obstructive sleep apnoea (OSA) on a asthma control in patients with difficult-to-control asthma. Participants will undergo home-based sleep studies to assess for OSA and are then allocated to one of three arms: 1) Patients with OSA treated with CPAP (intervention group), 2) Patients with OSA not treated for OSA (control group) and 3) Patients without OSA (reference group). The primary objective is to evaluate whether treating OSA improves asthma control, symptom burden, and quality of life compared to untreated OSA and to patients without OSA. Secondary outcomes include exacerbation rates, sleep quality, and healthcare utilization. This trial aims to clarify the contribution of OSA to poor asthma control and the potential benefits of integrated sleep and respiratory care in this complex population.
This description comes directly from the study's public registry record.
Laura Piggott, BM BS BSc MSc · +353876801786 · laurampiggott@gmail.com
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| St. James's Hospital | Dublin, Dublin, Ireland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07160868